| Human Genome Sciences Inc | Diagnostic Substances | $1.06B | ($3.73M) | $1.06B
 |
| Genzyme Corp | Biotechnology | -- | ($866.53M) | $866.53M
 |
| Valeant Pharmaceuticals International, Inc. | Drug Delivery | $109.76M | ($566.86M) | $676.61M
 |
| Micromet, Inc. | Biotechnology | $311.96M | ($742.88K) | $312.71M
 |
| Perrigo Co | Drug Related Products | ($29.03M) | ($263.11M) | $234.08M
 |
| Allos Therapeutics Inc | Drug Manufacturers - Other | $182.78M | ($298.35K) | $183.08M
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| Warner Chilcott Plc | Biotechnology | ($1.17B) | ($1.33B) | $157.37M
 |
| Forest Laboratories Inc | Drug Manufacturers - Other | $132.53M | ($6.33M) | $138.86M
 |
| Lexicon Pharmaceuticals, Inc./de | Diagnostic Substances | $136.74M | ($58.49K) | $136.80M
 |
| Inspire Pharmaceuticals Inc | Drug Manufacturers - Other | -- | ($119.02M) | $119.02M
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| United Therapeutics Corp | Drug Manufacturers - Other | ($16.57M) | ($119.10M) | $102.54M
 |
| Theravance Inc | Biotechnology | $210.50M | $118.13M | $92.37M
 |
| Amarin Corp Plc\uk | Drug Manufacturers - Other | ($138.14M) | ($217.75M) | $79.61M
 |
| Intermune Inc | Biotechnology | $271.21K | ($77.97M) | $78.24M
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| Obagi Medical Products, Inc. | Biotechnology | ($2.01M) | ($79.70M) | $77.68M
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| Incyte Corp | Biotechnology | $56.23M | ($15.67M) | $71.90M
 |
| Mannkind Corp | Biotechnology | $77.18M | $17.55M | $59.63M
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| Illumina Inc | Biotechnology | ($7.46M) | ($64.56M) | $57.10M
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| Questcor Pharmaceuticals Inc | Biotechnology | ($25.28M) | ($76.42M) | $51.14M
 |
| Amyris, Inc. | Biotechnology | $18.62M | ($20.65M) | $39.27M
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| China Biologic Products, Inc. | Biotechnology | $8.83M | ($27.54M) | $36.36M
 |
| Tesaro, Inc. | Biotechnology | $30.32M | -- | $30.32M
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| Amicus Therapeutics Inc | Biotechnology | $30.36M | $145.92K | $30.22M
 |
| Synta Pharmaceuticals Corp | Diagnostic Substances | $36.90M | $9.34M | $27.57M
 |
| Ista Pharmaceuticals Inc | Diagnostic Substances | ($10.11M) | ($34.49M) | $24.38M
 |
| Orchid Cellmark Inc | Diagnostic Substances | $23.30M | -- | $23.30M
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| Anadys Pharmaceuticals Inc | Biotechnology | -- | ($19.20M) | $19.20M
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| Auxilium Pharmaceuticals Inc | Drug Related Products | ($174.57K) | ($18.77M) | $18.59M
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| Hospira Inc | Drug Delivery | ($573.05K) | ($18.87M) | $18.30M
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| Dendreon Corp | Biotechnology | ($1.74M) | ($17.31M) | $15.57M
 |
| Par Pharmaceutical Companies, Inc. | Drugs - Generic | ($1.39M) | ($16.75M) | $15.35M
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| Cephalon Inc | Drug Manufacturers - Other | -- | ($15.16M) | $15.16M
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| Pharmacyclics Inc | Drug Manufacturers - Other | $29.82M | $14.81M | $15.01M
 |
| Targacept Inc | Biotechnology | $5.76M | ($9.13M) | $14.88M
 |
| Opko Health, Inc. | Drug Manufacturers - Other | $47.09M | $32.61M | $14.49M
 |
| Aveo Pharmaceuticals Inc | Biotechnology | ($695.90K) | ($14.84M) | $14.15M
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| Xoma Corp | Biotechnology | $14.05M | $16.90K | $14.03M
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| Vical Inc | Biotechnology | $11.92M | ($74.95K) | $11.99M
 |
| Talecris Biotherapeutics Holdings Corp. | Biotechnology | -- | ($9.85M) | $9.85M
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| Medicines Co /de | Drug Manufacturers - Other | ($3.37M) | ($13.02M) | $9.65M
 |
| Prolor Biotech, Inc. | Biotechnology | $5.02M | ($4.57M) | $9.59M
 |
| Emergent Biosolutions Inc. | Biotechnology | ($773.22K) | ($10.35M) | $9.58M
 |
| Endo Health Solutions Inc. | Drug Manufacturers - Other | ($15.88K) | ($8.79M) | $8.77M
 |
| Medicis Pharmaceutical Corp | Biotechnology | ($21.79M) | ($30.34M) | $8.55M
 |
| Idexx Laboratories Inc /de | Diagnostic Substances | ($32.18M) | ($40.50M) | $8.32M
 |
| Siga Technologies Inc | Drug Manufacturers - Other | ($137.64K) | ($7.90M) | $7.77M
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| Celgene Corp /de/ | Biotechnology | ($1.08M) | ($8.58M) | $7.50M
 |
| Inhibitex, Inc. | Biotechnology | ($739.62K) | ($8.23M) | $7.49M
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| Pain Therapeutics Inc | Drug Manufacturers - Other | -- | ($7.48M) | $7.48M
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| Anthera Pharmaceuticals Inc | Drug Manufacturers - Major | ($6.18M) | ($13.22M) | $7.03M
 |
| Galena Biopharma, Inc. | Biotechnology | $9.59K | ($7.02M) | $7.03M
 |
| Cytrx Corp | Biotechnology | $6.84M | -- | $6.84M
 |
| Charles River Laboratories International Inc | Biotechnology | ($5.31M) | ($11.81M) | $6.50M
 |
| Alkermes Inc | Drug Delivery | -- | ($6.49M) | $6.49M
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| Amag Pharmaceuticals Inc. | Diagnostic Substances | $6.35M | ($129.15K) | $6.48M
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| Acorda Therapeutics Inc | Biotechnology | ($1.84M) | ($8.12M) | $6.28M
 |
| Meridian Bioscience Inc | Diagnostic Substances | ($277.90K) | ($5.97M) | $5.69M
 |
| Orexigen Therapeutics, Inc. | Drug Manufacturers - Other | ($5.50M) | ($11.18M) | $5.68M
 |
| Dusa Pharmaceuticals Inc | Drug Manufacturers - Other | ($721.93K) | ($6.00M) | $5.28M
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| Lilly Eli & Co | Drug Manufacturers - Major | ($3.88M) | ($8.61M) | $4.73M
 |
| Zalicus Inc. | Biotechnology | ($80.28K) | ($4.26M) | $4.18M
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| Biodel Inc | Drug Manufacturers - Other | ($185.72K) | ($4.13M) | $3.95M
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| Cpex Pharmaceuticals, Inc. | Drug Manufacturers - Major | -- | ($3.91M) | $3.91M
 |
| Horizon Pharma, Inc. | Drug Manufacturers - Major | $17.36M | $13.60M | $3.76M
 |
| King Pharmaceuticals Inc | Drug Manufacturers - Other | -- | ($3.57M) | $3.57M
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| Tranzyme Inc | Drug Manufacturers - Major | $3.48M | $2.71K | $3.47M
 |
| Santarus Inc | Drug Manufacturers - Other | $3.11M | ($317.50K) | $3.42M
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| Neogen Corp | Diagnostic Substances | ($3.82M) | ($7.20M) | $3.37M
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| Momenta Pharmaceuticals Inc | Biotechnology | ($1.32M) | ($4.48M) | $3.16M
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| Regulus Therapeutics Inc. | Drug Manufacturers - Major | $3.00M | -- | $3.00M
 |
| Aeolus Pharmaceuticals, Inc. | Drug Manufacturers - Other | $101.68K | ($2.51M) | $2.61M
 |
| Response Genetics Inc | Diagnostic Substances | $2.20M | ($54.86K) | $2.25M
 |
| Keryx Biopharmaceuticals Inc | Drug Manufacturers - Major | ($133.08K) | ($2.37M) | $2.23M
 |
| Abaxis Inc | Diagnostic Substances | ($3.57M) | ($5.74M) | $2.17M
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| Aegerion Pharmaceuticals, Inc. | Drug Manufacturers - Major | ($17.04M) | ($19.13M) | $2.09M
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| Gtx Inc /de/ | Biotechnology | $2.37M | $360.65K | $2.01M
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| Lpath, Inc | Biotechnology | ($207.55K) | ($2.20M) | $2.00M
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| Depomed Inc | Drug Manufacturers - Other | $25.05K | ($1.94M) | $1.96M
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| Affymax Inc | Biotechnology | ($10.20M) | ($12.07M) | $1.87M
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| Immunogen Inc | Biotechnology | ($488.87K) | ($2.34M) | $1.85M
 |
| Schiff Nutrition International, Inc. | Drug Related Products | ($289.65K) | ($2.06M) | $1.77M
 |
| Pacific Biosciences Of California, Inc. | Biotechnology | $1.32M | ($240.82K) | $1.56M
 |
| Coronado Biosciences Inc | Biotechnology | $1.55M | -- | $1.55M
 |
| Kv Pharmaceutical Co /de/ | Drug Delivery | -- | ($1.50M) | $1.50M
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| Life Technologies Corp | Biotechnology | ($2.21M) | ($3.67M) | $1.46M
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| Neurogesx Inc | Drug Manufacturers - Other | $27.70K | ($1.39M) | $1.42M
 |
| Avanir Pharmaceuticals, Inc. | Drug Manufacturers - Other | ($884.06K) | ($2.21M) | $1.32M
 |
| Novabay Pharmaceuticals, Inc. | Drug Manufacturers - Other | $1.51M | $282.50K | $1.23M
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| Cypress Bioscience Inc | Biotechnology | -- | ($1.19M) | $1.19M
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| Palatin Technologies Inc | Diagnostic Substances | $0.62K | ($1.17M) | $1.17M
 |
| Cyclacel Pharmaceuticals, Inc. | Biotechnology | $7.87K | ($1.14M) | $1.15M
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| Spectrum Pharmaceuticals Inc | Drug Manufacturers - Major | $1.18M | $32.66K | $1.14M
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| Repros Therapeutics Inc. | Biotechnology | $3.06M | $1.97M | $1.09M
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| Impax Laboratories Inc | Biotechnology | ($2.32M) | ($3.40M) | $1.09M
 |
| Biospecifics Technologies Corp | Biotechnology | ($184.74K) | ($1.17M) | $985.03K
 |
| Furiex Pharmaceuticals, Inc. | Drug Manufacturers - Other | $17.47M | $16.56M | $916.86K
 |
| Bacterin International Holdings, Inc. | Biotechnology | $108.95K | ($789.26K) | $898.20K
 |
| Savient Pharmaceuticals Inc | Biotechnology | $2.37M | $1.47M | $897.61K
 |
| Alimera Sciences Inc | Drug Manufacturers - Major | ($101.05K) | ($973.54K) | $872.49K
 |
| Skystar Bio-Pharmaceutical Co | Drug Manufacturers - Major | $841.97K | -- | $841.97K
 |